Kiyofumi Ishikawa

Clearance of Circulating Endothelin-1 by ETB Receptors in Rats

Takahiro Fukuroda, Tatsuya Fujikawa, Satoshi Ozaki et al. · Biochemical and Biophysical Research Communications · 1994 · 624 citations

Etb Receptors, Medicine, Physiology +4

Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788.

Kiyofumi Ishikawa, M. Ihara, Kazuhito Noguchi et al. · Proceedings of the National Academy of Sciences · 1994 · 573 citations · Full text

Molecular Pharmacology, Eta-selective Antagonist, Functional Selectivity +13

Synthesis of 1,4-Dithiafulvenes and 1,4-Dithiafulvalenes by Carbonyl Olefination Using 2-Dimethoxyphosphinyl-1,3-benzodithiole

Kin‐ya Akiba, Kiyofumi Ishikawa, Naoki Inamoto · Bulletin of the Chemical Society of Japan · 1978 · 149 citations

Carbonyl Olefination Using, Derivative (Chemistry), Derivatives +14

Cyclic pentapeptide endothelin antagonists with high ETA selectivity. Potency- and solubility-enhancing modifications

Kiyofumi Ishikawa, Takehiro Fukami, Toshio Nagase et al. · Journal of Medicinal Chemistry · 1992 · 140 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Science +14

Antihypertensive effect of a newly synthesized endothelin antagonist, BQ-123, in a genetic hypertensive model

Masaru Nishikibe, Sonoko Tsuchida, Megumu Okada et al. · Life Sciences · 1993 · 122 citations

Hypertension, Genetic Hypertensive Model, Endothelin Antagonist +8