Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788.

Kiyofumi Ishikawa, M. Ihara, Kazuhito Noguchi, +7

Proceedings of the National Academy of Sciences

Molecular PharmacologyEta-selective AntagonistFunctional SelectivityMedicineVascular Pharmacology +11

Potent neuropeptide Y Y1 receptor antagonist, 1229U91: blockade of neuropeptide Y-induced and physiological food intake.

Akio Kanatani, Akane Ishihara, Shuichi Asahi, +3

Endocrinology

NutritionIntracerebroventricular InjectionFood IntakeGastrointestinal Peptide HormoneMolecular Pharmacology +16

ETB-Mediated Regulation of Extracellular Levels of Endothelin-1 in Cultured Human Endothelial Cells

Satoshi Ozaki, Kenji Ohwaki, M. Ihara, +3

Biochemical and Biophysical Research Communications

InflammationSignal TransductionAngiogenesisEtb-mediated RegulationCell Signaling +11

A potent neuropeptide Y antagonist, 1229U91, suppressed spontaneous food intake in Zucker fatty rats

Akane Ishihara, Takeshi Tanaka, Akio Kanatani, +3

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

NutritionFood IntakeGastrointestinal Peptide HormoneObesityMetabolic Syndrome +18

Two Endothelin Receptor Subtypes in Porcine Arteries

M. Ihara, Toshihiko Saeki, Kaoru Funabashi, +6

Journal of Cardiovascular Pharmacology

Porcine ArteriesVascular DiseaseMolecular PhysiologyCardiovascular DiseaseMedicine +13

Coexpression Studies with Endothelin Receptor Subtypes Indicate the Existence of Intracellular Cross-Talk between ETA and ETB Receptors

Satoshi Ozaki, Kenji Ohwaki, M. Ihara, +2

The Journal of Biochemistry

Comparative effects of short- and long-term feeding of safflower oil and perilla oil on lipid metabolism in rats

M. Ihara, Hayato Umekawa, Takao Takahashi, +1

Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology

NutritionLipid MetabolismOmega-3 Fatty AcidMedicineLipid Nutrition +6

Endothelin ETB receptors couple to two distinct signaling pathways in porcine kidney epithelial LLC-PK1 cells.

Satoshi Ozaki, M. Ihara, Toshihiko Saeki, +3

Journal of Pharmacology and Experimental Therapeutics

Increased endothelin-1 binding sites in the cardiac membranes in rats with chronic heart failure.

T. Miyauchi, S. SAKAI, M. Ihara, +4

PubMed

CardiomyopathyHeart FailureMolecular PhysiologyChronic Heart FailureCardiovascular Disease +13