Eduardo José Nepomuceno Montenegro

Characterization of the Cephalosporium acremonium pcbAB gene encoding alpha-aminoadipyl-cysteinyl-valine synthetase, a large multidomain peptide synthetase: linkage to the pcbC gene as a cluster of early cephalosporin biosynthetic genes and evidence of multiple functional domains

Santiago Gutiérrez, Begoña Díez, Eduardo José Nepomuceno Montenegro · Journal of Bacteriology · 1991 · 180 citations · Full text

Pcbc Gene, Molecular Biology, Alpha-aminoadipyl-cysteinyl-valine Synthetase +18

Mutants blocked in penicillin biosynthesis show a deletion of the entire penicillin gene cluster at a specific site within a conserved hexanucleotide sequence

Francisco Fierro, Eduardo José Nepomuceno Montenegro, Santiago Gutiérrez · Applied Microbiology and Biotechnology · 1996 · 90 citations

Penicillin Biosynthesis Show, Antimicrobial Resistance Gene, Health Sciences +14

The isopenicillin‐N acyltransferase of <i>Penicillium chrysogenum</i> has isopenicillin‐N amidohydrolase, 6‐aminopenicillanic acid acyltransferase and penicillin amidase activities, all of which are encoded by the single <i>penDE</i> gene

Emilio Fernández Álvarez, Boudewijn Meesschaert, Eduardo José Nepomuceno Montenegro et al. · European Journal of Biochemistry · 1993 · 84 citations · Full text

Cloning, characterization of the acyl-CoA : 6-amino penicillanic acid acyltransferase gene of Aspergillus nidulans and linkage to the isopenicillin N synthase gene

Eduardo José Nepomuceno Montenegro, José Luis Barredo, Santiago Gutiérrez et al. · Molecular and General Genetics MGG · 1990 · 62 citations

Biosynthesis, Biotransformation, Biochemistry +3

Catabolism of lysine in Penicillium chrysogenum leads to formation of 2-aminoadipic acid, a precursor of penicillin biosynthesis

Cristina Esmahan, Emilio Fernández Álvarez, Eduardo José Nepomuceno Montenegro · Applied and Environmental Microbiology · 1994 · 41 citations · Full text

Engineering, Penicillin Production, Penicillin Biosynthesis +16