John R. Ferrarone

Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells

Arun M. Unni, Bryant Harbourne, Min Hee Oh et al. · eLife · 2018 · 114 citations · Full text

Medicine, Cancer Biology, Oncology +17

Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene <i>U2af1</i>

Dennis Liang Fei, Tao Zhen, Benjamin H. Durham et al. · Proceedings of the National Academy of Sciences · 2018 · 73 citations · Full text

Medicine, Hematology, Oncology +15

GCN2 kinase activation by ATP-competitive kinase inhibitors

Colin P. Tang, Owen Clark, John R. Ferrarone et al. · Nature Chemical Biology · 2021 · 57 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma

Benjamin D. Stein, John R. Ferrarone, Eric E. Gardner et al. · Cancer Discovery · 2023 · 38 citations · Full text

Life Sciences, Genetics, Oncology +14

Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells

Fraser Johnson, John R. Ferrarone, Alvin Liu et al. · Cell Reports · 2022 · 30 citations · Full text

Life Sciences, Molecular Biology, Oncology +16