Owen Clark

An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells

Dan Rohle, Janeta Popovici-Müller, Nicolaos Palaskas et al. · Science · 2013 · 1.1K citations · Full text

Cancer Biology, Glioma, Tumor Biology +16

Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma

Christian Grommes, Alessandro Pastore, Nicolaos Palaskas et al. · Cancer Discovery · 2017 · 390 citations · Full text

GCN2 kinase activation by ATP-competitive kinase inhibitors

Colin P. Tang, Owen Clark, John R. Ferrarone et al. · Nature Chemical Biology · 2021 · 54 citations · Full text

Signal Transduction, Biochemistry, G Protein-coupled Receptor +9

Tyrosine phosphatase inhibitors combined with retinoic acid can enhance differentiation of neuroblastoma cells and trigger ERK- and AKT-dependent, p53-independent senescence

Owen Clark, Shruti Daga, Andrew W. Stoker · Cancer Letters · 2012 · 35 citations

Medicine, Receptor Tyrosine Kinase, Retinoic Acid +9

Oxovanadium-based inhibitors can drive redox-sensitive cytotoxicity in neuroblastoma cells and synergise strongly with buthionine sulfoximine

Owen Clark, Inhye Park, Alessia Di Florio et al. · Cancer Letters · 2014 · 16 citations · Full text

Apoptosis, Cell Death, Pharmacotherapy +16