In vivo gene editing in dystrophic mouse muscle and muscle stem cells

Mohammadsharif Tabebordbar, Kexian Zhu, Jason Cheng, +12

Science

In Vivo Gene TherapyMolecular BiologyRegenerative MedicineSkeletal MuscleDmd Gene +17

A multifunctional AAV–CRISPR–Cas9 and its host response

Wei Leong Chew, Mohammadsharif Tabebordbar, Jason Cheng, +6

Nature Methods

Multifunctional Aav–crispr–cas9Natural SciencesGenetic EngineeringMolecular BiologyGenome Engineering +4

dCas9-based gene editing for cleavage-free genomic knock-in of long sequences

Chengkun Wang, Yuanhao Qu, Jason Cheng, +4

Nature Cell Biology

Analysis of varicella zoster virus attenuation by evaluation of chimeric parent Oka/vaccine Oka recombinant viruses in skin xenografts in the SCIDhu mouse model

Leigh Zerboni, Stewart Hinchliffe, Marvin Sommer, +8

Virology

VaccinationMolecular VirologyPathogenesisImmunologyPathology +7

In Situ Modification of Tissue Stem and Progenitor Cell Genomes

Jill M. Goldstein, Mohammadsharif Tabebordbar, Kexian Zhu, +13

Cell Reports

Microbial single-strand annealing proteins enable CRISPR gene-editing tools with improved knock-in efficiencies and reduced off-target effects

Chengkun Wang, Jason Cheng, Qianhe Zhang, +4

Nucleic Acids Research

Reduced Off-target EffectsEngineeringBiomolecular ToolGeneticsMolecular Biology +18

Mutagenesis of Varicella-Zoster Virus Glycoprotein I (gI) Identifies a Cysteine Residue Critical for gE/gI Heterodimer Formation, gI Structure, and Virulence in Skin Cells

Stefan L. Oliver, Marvin Sommer, Mike Reichelt, +7

Journal of Virology

Vzv PathogenesisSkin CellsVirus StructureVaricella-zoster Virus GlycoproteinMolecular Virology +10

Direct identification of ventrointermediate nucleus of the thalamus on magnetic resonance and computed tomography images

Arun-Angelo Patil, Thomas Falloon, Francis J. Hahn, +2

Surgical Neurology

Direct IdentificationNeuroimaging ModalityMedical ImagingVentrointermediate NucleusNeuroanatomy +12

CRISPR-Cas12a System With Synergistic Phage Recombination Proteins for Multiplex Precision Editing in Human Cells

Chengkun Wang, Qiong Xia, Qianhe Zhang, +5

Frontiers in Cell and Developmental Biology