Géraldine San Jose

Antibacterial and antitubercular activity of fosmidomycin, FR900098, and their lipophilic analogs

Eugene Uh, Emily R. Jackson, Géraldine San Jose et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 68 citations

Antitubercular Activity, Antimicrobial Susceptibility, Antibiotics +10

Lipophilic Prodrugs of FR900098 Are Antimicrobial against Francisella novicida In Vivo and In Vitro and Show GlpT Independent Efficacy

Elizabeth S. McKenney, Michelle A. Sargent, Hameed Ullah Khan et al. · PLoS ONE · 2012 · 45 citations · Full text

Structure–Activity Relationships of the MEPicides: <i>N</i>-Acyl and <i>O</i>-Linked Analogs of FR900098 as Inhibitors of Dxr from <i>Mycobacterium tuberculosis</i> and <i>Yersinia pestis</i>

Géraldine San Jose, Emily R. Jackson, Amanda Haymond et al. · ACS Infectious Diseases · 2016 · 31 citations · Full text

Design of potential bisubstrate inhibitors against Mycobacterium tuberculosis (Mtb) 1-deoxy-d-xylulose 5-phosphate reductoisomerase (Dxr)—evidence of a novel binding mode

Géraldine San Jose, Emily R. Jackson, Eugene Uh et al. · MedChemComm · 2013 · 29 citations · Full text

The effect of chain length and unsaturation on Mtb Dxr inhibition and antitubercular killing activity of FR900098 analogs

Emily R. Jackson, Géraldine San Jose, Robert C. Brothers et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 26 citations · Full text

Chain Length, Medicine, Drug Discovery +5