Géraldine San Jose

Antibacterial and antitubercular activity of fosmidomycin, FR900098, and their lipophilic analogs

Eugene Uh, Emily R. Jackson, Géraldine San Jose et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 69 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Lipophilic Prodrugs of FR900098 Are Antimicrobial against Francisella novicida In Vivo and In Vitro and Show GlpT Independent Efficacy

Elizabeth S. McKenney, Michelle A. Sargent, Hameed Ullah Khan et al. · PLoS ONE · 2012 · 45 citations · Full text

Life Sciences, Biochemistry, Microbiology +12

Structure–Activity Relationships of the MEPicides: <i>N</i>-Acyl and <i>O</i>-Linked Analogs of FR900098 as Inhibitors of Dxr from <i>Mycobacterium tuberculosis</i> and <i>Yersinia pestis</i>

Géraldine San Jose, Emily R. Jackson, Amanda Haymond et al. · ACS Infectious Diseases · 2016 · 31 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Design of potential bisubstrate inhibitors against Mycobacterium tuberculosis (Mtb) 1-deoxy-d-xylulose 5-phosphate reductoisomerase (Dxr)—evidence of a novel binding mode

Géraldine San Jose, Emily R. Jackson, Eugene Uh et al. · MedChemComm · 2013 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

The effect of chain length and unsaturation on Mtb Dxr inhibition and antitubercular killing activity of FR900098 analogs

Emily R. Jackson, Géraldine San Jose, Robert C. Brothers et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7