Amanda Haymond

Synthesis and Bioactivity of β-Substituted Fosmidomycin Analogues Targeting 1-Deoxy-<scp>d</scp>-xylulose-5-phosphate Reductoisomerase

René Chofor, Sanjeewani Sooriyaarachchi, Martijn Risseeuw et al. · Journal of Medicinal Chemistry · 2015 · 40 citations · Full text

MEPicides: α,β-Unsaturated Fosmidomycin Analogues as DXR Inhibitors against Malaria

Xu Wang, Rachel L. Edwards, Haley Ball et al. · Journal of Medicinal Chemistry · 2018 · 36 citations · Full text

Structure–Activity Relationships of the MEPicides: <i>N</i>-Acyl and <i>O</i>-Linked Analogs of FR900098 as Inhibitors of Dxr from <i>Mycobacterium tuberculosis</i> and <i>Yersinia pestis</i>

Géraldine San Jose, Emily R. Jackson, Amanda Haymond et al. · ACS Infectious Diseases · 2016 · 31 citations · Full text

Design of potential bisubstrate inhibitors against Mycobacterium tuberculosis (Mtb) 1-deoxy-d-xylulose 5-phosphate reductoisomerase (Dxr)—evidence of a novel binding mode

Géraldine San Jose, Emily R. Jackson, Eugene Uh et al. · MedChemComm · 2013 · 29 citations · Full text

The effect of chain length and unsaturation on Mtb Dxr inhibition and antitubercular killing activity of FR900098 analogs

Emily R. Jackson, Géraldine San Jose, Robert C. Brothers et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 26 citations · Full text

Chain Length, Medicine, Drug Discovery +5