Robert C. Brothers

MEPicides: α,β-Unsaturated Fosmidomycin Analogues as DXR Inhibitors against Malaria

Xu Wang, Rachel L. Edwards, Haley Ball et al. · Journal of Medicinal Chemistry · 2018 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis

Rachel L. Edwards, Robert C. Brothers, Xu Wang et al. · Scientific Reports · 2017 · 37 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure–Activity Relationships of the MEPicides: <i>N</i>-Acyl and <i>O</i>-Linked Analogs of FR900098 as Inhibitors of Dxr from <i>Mycobacterium tuberculosis</i> and <i>Yersinia pestis</i>

Géraldine San Jose, Emily R. Jackson, Amanda Haymond et al. · ACS Infectious Diseases · 2016 · 31 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

The effect of chain length and unsaturation on Mtb Dxr inhibition and antitubercular killing activity of FR900098 analogs

Emily R. Jackson, Géraldine San Jose, Robert C. Brothers et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7

Design, synthesis, and evaluation of substituted nicotinamide adenine dinucleotide (NAD+) synthetase inhibitors as potential antitubercular agents

Xu Wang, Yong‐Mo Ahn, Adam G. Lentscher et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 22 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +15