A.C. Guardia

Encoded Library Technology as a Source of Hits for the Discovery and Lead Optimization of a Potent and Selective Class of Bactericidal Direct Inhibitors of <i>Mycobacterium tuberculosis</i> InhA

Lourdes Encinas, Heather P. O’Keefe, Margarete Neu et al. · Journal of Medicinal Chemistry · 2014 · 118 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

<i>N</i>‐Benzyl‐4‐((heteroaryl)methyl)benzamides: A New Class of Direct NADH‐Dependent 2‐<i>trans</i> Enoyl–Acyl Carrier Protein Reductase (InhA) Inhibitors with Antitubercular Activity

A.C. Guardia, Gülçin Gülten, Raquel Fernández-García et al. · ChemMedChem · 2016 · 40 citations

Life Sciences, Medicinal Chemistry, Pharmacology +14

Evaluation of five DNA extraction methods for detection of H. pylori in formalin-fixed paraffin-embedded (FFPE) liver tissue from patients with hepatocellular carcinoma

Elizabeth Maria Afonso Rabelo‐Gonçalves, Bruna Maria Röesler, A.C. Guardia et al. · Pathology - Research and Practice · 2013 · 34 citations

Medicine, Molecular Biology, Pathology +15

Easy-To-Synthesize Spirocyclic Compounds Possess Remarkable in Vivo Activity against <i>Mycobacterium tuberculosis</i>

A.C. Guardia, Jessica Baiget, Mónica Cacho et al. · Journal of Medicinal Chemistry · 2018 · 31 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

A Focused Screen Identifies Antifolates with Activity on <i>Mycobacterium tuberculosis</i>

Anuradha Kumar, A.C. Guardia, Gonzalo Colmenarejo et al. · ACS Infectious Diseases · 2015 · 28 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14