Early Phenotypic Changes in Transgenic Mice That Overexpress Different Mutants of Amyloid Precursor Protein in Brain

Dieder Moechars, Ilse Dewachter, Kristin Lorent, +10

Journal of Biological Chemistry

Prominent Axonopathy in the Brain and Spinal Cord of Transgenic Mice Overexpressing Four-Repeat Human tau Protein

Kurt Spittaels, Chris Van den Haute, Jo Van Dorpe, +9

American Journal Of Pathology

Neurodegenerative DiseasesNeuroanatomyDegenerative DiseaseDegenerative PathologyProminent Axonopathy +6

Glycogen Synthase Kinase-3β Phosphorylates Protein Tau and Rescues the Axonopathy in the Central Nervous System of Human Four-repeat Tau Transgenic Mice

Kurt Spittaels, Chris Van den Haute, Jo Van Dorpe, +12

Journal of Biological Chemistry

Expression of Human Apolipoprotein E4 in Neurons Causes Hyperphosphorylation of Protein Tau in the Brains of Transgenic Mice

Ina Tesseur, Jo Van Dorpe, Kurt Spittaels, +3

American Journal Of Pathology

Knockout MouseNeurodegenerative DiseasesSignal TransductionMolecular NeuroscienceAlzheimer's Disease +9

Neuronal Deficiency of Presenilin 1 Inhibits Amyloid Plaque Formation and Corrects Hippocampal Long-Term Potentiation But Not a Cognitive Defect of Amyloid Precursor Protein [V717I] Transgenic Mice

Ilse Dewachter, Delphine Reversé, Nathalie Caluwaerts, +11

Journal of Neuroscience

Prominent Cerebral Amyloid Angiopathy in Transgenic Mice Overexpressing the London Mutant of Human APP in Neurons

Jo Van Dorpe, Liesbet Smeijers, Ilse Dewachter, +14

American Journal Of Pathology

London MutantNeurodegenerative DiseasesAlzheimer's DiseaseMedicineNeurochemical Biomarkers +8

The Orphan G Protein–Coupled Receptor 3 Modulates Amyloid-Beta Peptide Generation in Neurons

Amantha Thathiah, Kurt Spittaels, Marcel Hoffmann, +11

Science

Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway

Cary Esselens, Viola Oorschot, Veerle Baert, +8

The Journal of Cell Biology

Peroxisome Proliferator-Activated Receptor γ Induces a Clearance Mechanism for the Amyloid-β Peptide

Ira Espuny-Camacho, Lutgarde Serneels, Kurt Spittaels, +3

Journal of Neuroscience

Insect neuropeptide F (NPF)-related peptides: Isolation from colorado potato beetle (Leptinotarsa decemlineata) brain

Kurt Spittaels, Peter Verhaert, Chris Shaw, +4

Insect Biochemistry and Molecular Biology

BiologyNeuroanatomyEntomologyColorado Potato BeetleNeuropeptide Receptor +7