Kurt Spittaels

Early Phenotypic Changes in Transgenic Mice That Overexpress Different Mutants of Amyloid Precursor Protein in Brain

Dieder Moechars, Ilse Dewachter, Kristin Lorent et al. · Journal of Biological Chemistry · 1999 · 666 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Prominent Axonopathy in the Brain and Spinal Cord of Transgenic Mice Overexpressing Four-Repeat Human tau Protein

Kurt Spittaels, Chris Van den Haute, Jo Van Dorpe et al. · American Journal Of Pathology · 1999 · 378 citations · Full text

Life Sciences, Neurobiology, Neuroscience +11

Glycogen Synthase Kinase-3β Phosphorylates Protein Tau and Rescues the Axonopathy in the Central Nervous System of Human Four-repeat Tau Transgenic Mice

Kurt Spittaels, Chris Van den Haute, Jo Van Dorpe et al. · Journal of Biological Chemistry · 2000 · 317 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Expression of Human Apolipoprotein E4 in Neurons Causes Hyperphosphorylation of Protein Tau in the Brains of Transgenic Mice

Ina Tesseur, Jo Van Dorpe, Kurt Spittaels et al. · American Journal Of Pathology · 2000 · 240 citations · Full text

Life Sciences, Neurobiology, Neuroscience +13

Neuronal Deficiency of Presenilin 1 Inhibits Amyloid Plaque Formation and Corrects Hippocampal Long-Term Potentiation But Not a Cognitive Defect of Amyloid Precursor Protein [V717I] Transgenic Mice

Ilse Dewachter, Delphine Reversé, Nathalie Caluwaerts et al. · Journal of Neuroscience · 2002 · 238 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17