Early Phenotypic Changes in Transgenic Mice That Overexpress Different Mutants of Amyloid Precursor Protein in Brain

Dieder Moechars, Ilse Dewachter, Kristin Lorent, +10

Journal of Biological Chemistry

Neuron-Specific Apolipoprotein E4 Proteolysis Is Associated with Increased Tau Phosphorylation in Brains of Transgenic Mice

Walter J. Brecht, Faith M. Harris, Shengjun Chang, +9

Journal of Neuroscience

Cell DeathTransgenic MiceSocial SciencesNeuroinflammationAlzheimer's Disease +22

Loss of TGF-β1 Leads to Increased Neuronal Cell Death and Microgliosis in Mouse Brain

Thomas C. Brionne, Ina Tesseur, Eliezer Masliah, +1

Neuron

Neurodegenerative DiseasesMolecular NeuroscienceMedicineNeuronal Cell DeathCell Death +9

The Disintegrin/Metalloproteinase ADAM10 Is Essential for the Establishment of the Brain Cortex

Ellen Jorissen, Johannes Prox, Christian Bernreuther, +13

Journal of Neuroscience

Deficiency in neuronal TGF-β signaling promotes neurodegeneration and Alzheimer’s pathology

Ina Tesseur, Kun Zou, Luke Esposito, +10

Journal of Clinical Investigation

Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice

Faith M. Harris, Walter J. Brecht, Qin Xu, +11

Proceedings of the National Academy of Sciences

Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain

Ira Espuny-Camacho, Amaia M. Arranz, Mark Fiers, +17

Neuron

Neurodegenerative DiseasesAlzheimer's DiseaseMedicineStem Cell ResearchMouse Brain +9

Expression of Human Apolipoprotein E4 in Neurons Causes Hyperphosphorylation of Protein Tau in the Brains of Transgenic Mice

Ina Tesseur, Jo Van Dorpe, Kurt Spittaels, +3

American Journal Of Pathology

Knockout MouseNeurodegenerative DiseasesSignal TransductionMolecular NeuroscienceAlzheimer's Disease +9

Prominent Cerebral Amyloid Angiopathy in Transgenic Mice Overexpressing the London Mutant of Human APP in Neurons

Jo Van Dorpe, Liesbet Smeijers, Ilse Dewachter, +14

American Journal Of Pathology

London MutantNeurodegenerative DiseasesAlzheimer's DiseaseMedicineNeurochemical Biomarkers +8

Prominent Axonopathy and Disruption of Axonal Transport in Transgenic Mice Expressing Human Apolipoprotein E4 in Neurons of Brain and Spinal Cord

Ina Tesseur, Jo Van Dorpe, Koen Bruynseels, +4

American Journal Of Pathology

Neurodegenerative DiseasesDevelopmental BiologyMolecular NeuroscienceNeuroanatomyAxonal Transport +9