Sneha Sanghavi

Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia

Shruti Bhatt, Marissa S. Pioso, Elyse A. Olesinski et al. · Cancer Cell · 2020 · 174 citations · Full text

Life Sciences, Cancer Biology, Cell Biology +16

Rescue Screens with Secreted Proteins Reveal Compensatory Potential of Receptor Tyrosine Kinases in Driving Cancer Growth

Fred Harbinski, Vanessa J. Craig, Sneha Sanghavi et al. · Cancer Discovery · 2012 · 107 citations

Medicine, Molecular Biology, Oncology +17

Recurrent ubiquitin B silencing in gynecological cancers establishes dependence on ubiquitin C

Alexia T. Kedves, Scott Gleim, Xiaoyou Liang et al. · Journal of Clinical Investigation · 2017 · 32 citations · Full text

Medicine, Cancer Biology, Oncology +15

Abstract 4477: MIK665/S64315, a novel Mcl-1 inhibitor, in combination with Bcl-2 inhibitors exhibits strong synergistic antitumor activity in a range of hematologic malignancies

Ensar Halilovic, Maïa Chanrion, Prakash Mistry et al. · Cancer Research · 2019 · 11 citations

Medicine, Oncology, Pharmacology +16

Abstract 1276: Identification of S65487/VOB560 as a potent and selective intravenous 2nd-generation BCL-2 inhibitor active in wild-type and clinical mutants resistant to Venetoclax

Arnaud LeTiran, Audrey Clapéron, James Davidson et al. · Cancer Research · 2021 · 11 citations

Medicine, Oncology, Pharmacology +16