Benjamin Bader

Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS–SOS1 interaction

R.C. Hillig, Brice Sautier, Jens Schroeder et al. · Proceedings of the National Academy of Sciences · 2019 · 379 citations · Full text

Medicine, Molecular Biology, Oncology +17

G Protein-Coupled Receptor 30 Localizes to the Endoplasmic Reticulum and Is Not Activated by Estradiol

Christiane Otto, Beate Rohde-Schulz, Gilda Schwarz et al. · Endocrinology · 2008 · 253 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17

The Novel ATR Inhibitor BAY 1895344 Is Efficacious as Monotherapy and Combined with DNA Damage–Inducing or Repair–Compromising Therapies in Preclinical Cancer Models

Antje M. Wengner, Gerhard Siemeister, Ulrich Lücking et al. · Molecular Cancer Therapeutics · 2019 · 210 citations

Medicine, Molecular Biology, Oncology +17

Affinity Map of Bromodomain Protein 4 (BRD4) Interactions with the Histone H4 Tail and the Small Molecule Inhibitor JQ1

Marie Jung, Martin Philpott, Susanne Müller et al. · Journal of Biological Chemistry · 2014 · 162 citations · Full text

Life Sciences, Chemical Biology, Molecular Biology +15

Bioorganic synthesis of lipid-modified proteins for the study of signal transduction

Benjamin Bader, Karsten Kuhn, David J. Owen et al. · Nature · 2000 · 159 citations

Life Sciences, Biochemistry, Biotechnology +12