B Filippi

Metformin activates a duodenal Ampk–dependent pathway to lower hepatic glucose production in rats

Frank A. Duca, Clémence D. Côté, Brittany A. Rasmussen et al. · Nature Medicine · 2015 · 386 citations · Full text

Hepatology, Biochemistry, Hepatic Glucose Production +11

Structure of the LKB1-STRAD-MO25 Complex Reveals an Allosteric Mechanism of Kinase Activation

Elton Zeqiraj, B Filippi, Mária Deák et al. · Science · 2009 · 353 citations

Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network

Clémence D. Côté, Brittany A. Rasmussen, Frank A. Duca et al. · Nature Medicine · 2015 · 145 citations

Insulin Resistance, Metabolic Syndrome, Systems Biology +13

ATP and MO25α Regulate the Conformational State of the STRADα Pseudokinase and Activation of the LKB1 Tumour Suppressor

Elton Zeqiraj, B Filippi, Simon Goldie et al. · PLoS Biology · 2009 · 143 citations · Full text

Molecular Regulation, Closed Conformation, Molecular Biology +22

MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases

B Filippi, Paola de los Heros, Youcef Mehellou et al. · The EMBO Journal · 2011 · 137 citations · Full text

Signal Transduction, Signaling Pathway, Receptor Tyrosine Kinase +5