Paola de los Heros

Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases

José Ponce‐Coria, Pedro San‐Cristobal, Kristopher T. Kahle et al. · Proceedings of the National Academy of Sciences · 2008 · 215 citations · Full text

Xenopus Laevis Oocytes, Immunology, Cellular Physiology +17

WNK3 modulates transport of Cl ^- in and out of cells: Implications for control of cell volume and neuronal excitability

Kristopher T. Kahle, Jesse Rinehart, Paola de los Heros et al. · Proceedings of the National Academy of Sciences · 2005 · 214 citations · Full text

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+–Cl− co-transporters

Paola de los Heros, Dario R. Alessi, Robert Gourlay et al. · Biochemical Journal · 2014 · 208 citations · Full text

Molecular Regulation, Kinase Inhibitors, Molecular Biology +19

Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways

Ciarán Richardson, Kei Sakamoto, Paola de los Heros et al. · Journal of Cell Science · 2011 · 182 citations · Full text

Hypertension Syndrome, Cellular Physiology, -Independent Pathways +22

WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl ^- cotransporters required for normal blood pressure homeostasis

Jesse Rinehart, Kristopher T. Kahle, Paola de los Heros et al. · Proceedings of the National Academy of Sciences · 2005 · 181 citations · Full text