Youcef Mehellou

The CUL3–KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction

Akihito Ohta, Frances‐Rose Schumacher, Youcef Mehellou et al. · Biochemical Journal · 2013 · 219 citations · Full text

Hypertension Syndrome Interacts, Genetics, Immunology +16

SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation

Jacob Thastrup, Fatema H. Rafiqi, Alberto C. Vitari et al. · Biochemical Journal · 2011 · 139 citations · Full text

MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases

B Filippi, Paola de los Heros, Youcef Mehellou et al. · The EMBO Journal · 2011 · 137 citations · Full text

Signal Transduction, Signaling Pathway, Receptor Tyrosine Kinase +5

Niclosamide, a Drug with Many (Re)purposes

Hachemi Kadri, Olivia A. Lambourne, Youcef Mehellou · ChemMedChem · 2018 · 116 citations · Full text

Antiparasitic Agent, True Hit, Immunology +18

Kinetin Riboside and Its ProTides Activate the Parkinson’s Disease Associated PTEN-Induced Putative Kinase 1 (PINK1) Independent of Mitochondrial Depolarization

Laura Osgerby, Yu‐Chiang Lai, Peter J. Thornton et al. · Journal of Medicinal Chemistry · 2017 · 94 citations · Full text

Mitophagy, Bioorganic Chemistry, Kinetin Riboside +16