Mark Stanley

GDC-0449—A potent inhibitor of the hedgehog pathway

Kirk Robarge, Shirley A. Brunton, Georgette M. Castanedo et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 385 citations · Full text

Molecular Pharmacology, Signaling Pathway, Molecular Pathway +6

Conformationally defined neurotransmitter analogs. Selective inhibition of glutamate uptake by one pyrrolidine-2,4-dicarboxylate diastereomer

Richard J. Bridges, Mark Stanley, Michael W. Anderson et al. · Journal of Medicinal Chemistry · 1991 · 303 citations

A Designed Peptide Ligase for Total Synthesis of Ribonuclease A with Unnatural Catalytic Residues

David Y. Jackson, John P. Burnier, Clifford Quan et al. · Science · 1994 · 284 citations

Bioorganic Chemistry, Engineering, Engineered Variant +18

Generation of an LFA-1 Antagonist by the Transfer of the ICAM-1 Immunoregulatory Epitope to a Small Molecule

Thomas R. Gadek, Daniel J. Burdick, Robert S. McDowell et al. · Science · 2002 · 169 citations

Immunology, Immune Regulation, Immunodominance +18

Lead identification of novel and selective TYK2 inhibitors

Jun Liang, Vickie Tsui, Anne van Abbema et al. · European Journal of Medicinal Chemistry · 2013 · 122 citations · Full text

Medicinal Chemistry, Hit Identification, Biochemistry +6