Karen E. Christensen

High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice

Karen E. Christensen, Leonie G. Mikael, Kit‐Yi Leung et al. · American Journal of Clinical Nutrition · 2015 · 155 citations · Full text

Steatosis in Mice Is Associated with Gender, Folate Intake, and Expression of Genes of One-Carbon Metabolism

Karen E. Christensen, Qing Wu, Xiaoling Wang et al. · Journal of Nutrition · 2010 · 109 citations

Metabolic Syndrome, Biochemistry, One-carbon Metabolism +8

The MTHFD1 p.Arg653Gln variant alters enzyme function and increases risk for congenital heart defects

Karen E. Christensen, Charles Rohlicek, Grégor Andelfinger et al. · Human Mutation · 2008 · 107 citations

Heart Failure, Genetics, Molecular Biology +18

The molecular basis of glutamate formiminotransferase deficiency

John Hilton, Karen E. Christensen, David Watkins et al. · Human Mutation · 2003 · 67 citations

Disruption of the Mthfd1 Gene Reveals a Monofunctional 10-Formyltetrahydrofolate Synthetase in Mammalian Mitochondria

Karen E. Christensen, Harshila Patel, Uroš Kuzmanov et al. · Journal of Biological Chemistry · 2004 · 53 citations · Full text