Leila Mekkaoui

Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR

Sara Ghorashian, Anne Marijn Kramer, Shimobi Onuoha et al. · Nature Medicine · 2019 · 644 citations · Full text

Life Sciences, Immunology, Pediatrics +16

Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors

Frederick Arce Vargas, Andrew J.S. Furness, Isabelle Solomon et al. · Immunity · 2017 · 430 citations · Full text

Medicine, Immunology, Oncology +17

A highly compact epitope-based marker/suicide gene for easier and safer T-cell therapy

Brian Philip, Evangelia Kokalaki, Leila Mekkaoui et al. · Blood · 2014 · 401 citations

Life Sciences, Genetics, Molecular Biology +10

Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study

Annika Fendler, Lewis Au, Scott T.C. Shepherd et al. · Nature Cancer · 2021 · 89 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +11

Characterization of a Novel ACE2-Based Therapeutic with Enhanced Rather than Reduced Activity against SARS-CoV-2 Variants

Mathieu Ferrari, Leila Mekkaoui, F. Tudor Ilca et al. · Journal of Virology · 2021 · 41 citations · Full text

Pharmacy, Infectious Diseases, Pharmacology +17