Michael S. Poslusney

Author

Vanderbilt University Medical Center

Also Known As

M S Poslusney, Michael Poslusney, Michael S. Poslusney

Publications

496

Citations

H-Index

Concepts

All Affiliations

Vanderbilt University Medical Center Vanderbilt University AstraZeneca (United States)John F. Kennedy Center for the Performing Arts

About

Michael S. Poslusney is an author at Vanderbilt University Medical Center specializing in natural sciences, drug discovery, and medicinal chemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	2	2	133
2	Natural Sciences	2	2	54
3	Biochemistry	2	2	54
4	Chemical Biology	2	2	54
5	Social Sciences	1	1	102

Michael S. Poslusney

Publications

464

Citations

H-Index

Page 1

	Year	Citations
Selective Activation of M<sub>4</sub>Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents Michael Bubser, Thomas M. Bridges, Ditte Dencker, ACS Chemical Neuroscience	2014	150
Potentiation of M1 Muscarinic Receptor Reverses Plasticity Deficits and Negative and Cognitive Symptoms in a Schizophrenia Mouse Model Ayan Ghoshal, Jerri M. Rook, Jonathan W. Dickerson, Neuropsychopharmacology Synaptic PlasticityNeuropsychologyCognitive SymptomsPsychiatryMedicine	2015	102
Discovery of VU0467485/AZ13713945: An M<sub>4</sub> PAM Evaluated as a Preclinical Candidate for the Treatment of Schizophrenia Michael R. Wood, Meredith J. Noetzel, Bruce J. Melancon, ACS Medicinal Chemistry Letters	2016	54
Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT) Scott T. Harrison, Michael S. Poslusney, James Mulhearn, ACS Medicinal Chemistry Letters	2015	44
Challenges in the development of an M4 PAM in vivo tool compound: The discovery of VU0467154 and unexpected DMPK profiles of close analogs Michael R. Wood, Meredith J. Noetzel, Michael S. Poslusney, Bioorganic & Medicinal Chemistry Letters	2016	40
Spirocyclic replacements for the isatin in the highly selective, muscarinic M1 PAM ML137: The continued optimization of an MLPCN probe molecule Michael S. Poslusney, Bruce J. Melancon, Patrick R. Gentry, Bioorganic & Medicinal Chemistry Letters Combinatorial ChemistryContinued OptimizationMedicinal ChemistryDrug TargetBiochemistry	2013	31
Isatin replacements applied to the highly selective, muscarinic M1 PAM ML137: Continued optimization of an MLPCN probe molecule Bruce J. Melancon, Michael S. Poslusney, Patrick R. Gentry, Bioorganic & Medicinal Chemistry Letters Continued OptimizationMedicinal ChemistryIsatin ReplacementsBiochemistryNatural Sciences	2012	23
Optimization of 8-Hydroxyquinolines as Inhibitors of Catechol <i>O</i> -Methyltransferase Ingrid P. Buchler, Daniel Akuma, Vinh Au, Journal of Medicinal Chemistry	2018	20

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