Concepedia

Michael S. Poslusney

MS

8

Publications

464

Citations

8

H-Index

2012

Active since

Affiliations

Vanderbilt University Medical Center(Current)

Vanderbilt University

AstraZeneca (United States)

John F. Kennedy Center for the Performing Arts

Michael S. Poslusney is an author at Vanderbilt University Medical Center specializing in natural sciences, drug discovery, and medicinal chemistry.

Top concepts

Publications per year

2012–2018

8

Publications

8

Selective Activation of M<sub>4</sub>Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents

Michael Bubser, Thomas M. Bridges, Ditte Dencker et al. · ACS Chemical Neuroscience · 2014 · 150 citations · Full text

Potentiation of M1 Muscarinic Receptor Reverses Plasticity Deficits and Negative and Cognitive Symptoms in a Schizophrenia Mouse Model

Ayan Ghoshal, Jerri M. Rook, Jonathan W. Dickerson et al. · Neuropsychopharmacology · 2015 · 102 citations · Full text

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Discovery of VU0467485/AZ13713945: An M<sub>4</sub> PAM Evaluated as a Preclinical Candidate for the Treatment of Schizophrenia

Michael R. Wood, Meredith J. Noetzel, Bruce J. Melancon et al. · ACS Medicinal Chemistry Letters · 2016 · 54 citations · Full text

Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT)

Scott T. Harrison, Michael S. Poslusney, James Mulhearn et al. · ACS Medicinal Chemistry Letters · 2015 · 44 citations · Full text

Challenges in the development of an M4 PAM in vivo tool compound: The discovery of VU0467154 and unexpected DMPK profiles of close analogs

Michael R. Wood, Meredith J. Noetzel, Michael S. Poslusney et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 40 citations · Full text

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