Bruce J. Melancon

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α

Curtis A. Thorne, Alison Hanson, Judsen Schneider et al. · Nature Chemical Biology · 2010 · 472 citations · Full text

Signal Transduction, Signaling Pathway, Molecular Pathway +11

Structural insights into HDAC6 tubulin deacetylation and its selective inhibition

Y. Miyake, J.J. Keusch, Longlong Wang et al. · Nature Chemical Biology · 2016 · 286 citations · Full text

Biochemistry, Natural Sciences, Molecular Biology +3

Allosteric Modulation of Seven Transmembrane Spanning Receptors: Theory, Practice, and Opportunities for Central Nervous System Drug Discovery

Bruce J. Melancon, Corey R. Hopkins, Michael R. Wood et al. · Journal of Medicinal Chemistry · 2011 · 222 citations · Full text

Drug Target, Synaptic Transmission, Altmetric Attention Score +22

Selective Activation of M₄Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents

Michael Bubser, Thomas M. Bridges, Ditte Dencker et al. · ACS Chemical Neuroscience · 2014 · 150 citations · Full text

Antipsychotic Drug-Like Effects of the Selective M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator VU0152100

Nellie Byun, Michael Grannan, Michael Bubser et al. · Neuropsychopharmacology · 2014 · 119 citations · Full text

Psychiatry, Functional Selectivity, Medicine +9