Ippei Shimizu

p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload

Masanori Sano, Tohru Minamino, Haruhiro Toko et al. · Nature · 2007 · 885 citations

Cardiomyopathy, Heart Failure, Cardiovascular Disease +8

A crucial role for adipose tissue p53 in the regulation of insulin resistance

Tohru Minamino, Masayuki Orimo, Ippei Shimizu et al. · Nature Medicine · 2009 · 865 citations

Metabolic Remodeling, Insulin Signaling, Obesity +16

Vascular rarefaction mediates whitening of brown fat in obesity

Ippei Shimizu, Tamar Aprahamian, Ryosuke Kikuchi et al. · Journal of Clinical Investigation · 2014 · 415 citations · Full text

Complement C1q Activates Canonical Wnt Signaling and Promotes Aging-Related Phenotypes

Atsuhiko T. Naito, Tomokazu S. Sumida, Seitaro Nomura et al. · Cell · 2012 · 313 citations · Full text

Cytokine, Complement System, Signal Transduction +7

Senolytic vaccination improves normal and pathological age-related phenotypes and increases lifespan in progeroid mice

Masayoshi Suda, Ippei Shimizu, Goro Katsuumi et al. · Nature Aging · 2021 · 242 citations

Vaccinology, Vaccination, Vaccine Development +13