Masayuki Orimo

p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload

Masanori Sano, Tohru Minamino, Haruhiro Toko et al. · Nature · 2007 · 885 citations

Cardiomyopathy, Heart Failure, Cardiovascular Disease +8

A crucial role for adipose tissue p53 in the regulation of insulin resistance

Tohru Minamino, Masayuki Orimo, Ippei Shimizu et al. · Nature Medicine · 2009 · 865 citations

Metabolic Remodeling, Insulin Signaling, Obesity +16

Angiotensin II Induces Premature Senescence of Vascular Smooth Muscle Cells and Accelerates the Development of Atherosclerosis via a p21-Dependent Pathway

Takeshige Kunieda, Tohru Minamino, Junichiro Nishi et al. · Circulation · 2006 · 300 citations

Protective Role of SIRT1 in Diabetic Vascular Dysfunction

Masayuki Orimo, Tohru Minamino, Hideyuki Miyauchi et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2009 · 208 citations

Pathology, Diabetic Vascular Dysfunction, Metabolic Remodeling +21

Cellular Senescence Impairs Circadian Expression of Clock Genes In Vitro and In Vivo

Takeshige Kunieda, Tohru Minamino, Taro Katsuno et al. · Circulation Research · 2006 · 125 citations · Full text

Developmental Biology, Aging, Alertness +12