Denis T. Akan - Concepedia

Author

Denis T. Akan

Also Known As

D. Akan, Denis T. Akan

Publications

178

Citations

H-Index

Concepts

All Affiliations

Denis T. Akan is an author at Vanderbilt University specializing in signal transduction, molecular biology, and cell biology.

#	Concept	H-Index	Publications	Citations
1	Medicine	3	3	98
2	Natural Sciences	3	3	98
3	Cell Biology	3	3	98
4	Biochemistry	2	2	80
5	Cellular Physiology	1	1	18

Denis T. Akan

Publications

178

Citations

H-Index

Page 1

	Year	Citations
Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS Timothy R. Hodges, Jason R. Abbott, Andrew J. Little, Journal of Medicinal Chemistry Combinatorial ChemistryGtp-bound RasMolecular BiologyStructure-based OptimizationNew Series	2018	52
Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling Jason R. Abbott, Timothy R. Hodges, R. Nathan Daniels, Journal of Medicinal Chemistry	2018	41
Small Molecule–Mediated Activation of RAS Elicits Biphasic Modulation of Phospho-ERK Levels that Are Regulated through Negative Feedback on SOS1 Jennifer E. Howes, Denis T. Akan, Michael C. Burns, Molecular Cancer Therapeutics	2018	39
Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS Jason R. Abbott, Pratiq A. Patel, Jennifer E. Howes, ACS Medicinal Chemistry Letters Molecular BiologyChemical BiologyRas SignalingTumor BiologySignaling Pathway	2018	28
Small Molecule SOS1 Agonists Modulate MAPK and PI3K Signaling <i>via</i> Independent Cellular Responses Denis T. Akan, Jennifer E. Howes, Jiqing Sai, ACS Chemical Biology Pi3k SignalingMolecular RegulationMolecular BiologyRas SignalingCellular Physiology	2019	18

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