Tumor Microenvironments Direct the Recruitment and Expansion of Human Th17 Cells

Xinming Su, Jian Ye, Eddy C. Hsueh, +3

The Journal of Immunology

T-regulatory CellImmunologyBiological MicroenvironmentsImmunologic MechanismHuman Tils +16

Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance

Melissa A. Meyer, John Baer, Brett L. Knolhoff, +11

Nature Communications

Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer

Lucia D’Amico, Sahil Mahajan, Aude-Hélène Capietto, +11

The Journal of Experimental Medicine

Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development

Xianmin Luo, Yujie Fu, Andrew J. Loza, +15

Cell Reports

Developmental BiologyBone BiologyBone Morphogenic ProteinBone RemodelingBone Homeostasis +3

Breast cancer–derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironment

Xinming Su, Yalin Xu, Gregory C. Fox, +20

Journal of Clinical Investigation

Minimal Gm-csf ExpressionBreast OncologyTumoral Gm-csfImmunologyImmune Regulation +19

The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling

Xinming Su, Desiree H. Floyd, Alun D. Hughes, +20

Journal of Clinical Investigation

SclerostinOsteoclast FunctionAdenosine DiphosphateCellular PhysiologyOsteoporosis +22

Bone-Induced Expression of Integrin β3 Enables Targeted Nanotherapy of Breast Cancer Metastases

Michael H. Ross, Alison K. Esser, Gregory C. Fox, +18

Cancer Research

Antagonizing Integrin β3 Increases Immunosuppression in Cancer

Xinming Su, Alison K. Esser, Sarah R. Amend, +22

Cancer Research

Hedgehog Signaling Inhibition Blocks Growth of Resistant Tumors through Effects on Tumor Microenvironment

Emanuela Heller, Michelle A. Hurchla, Jingyu Xiang, +13

Cancer Research

Biological MicroenvironmentsCancer BiologyBone DevelopmentTumor BiologyHh Pathway +15

Human tumor‐infiltrating Th17 cells have the capacity to differentiate into IFN‐γ⁺ and FOXP3⁺ T cells with potent suppressive function

Jian Ye, Xinming Su, Eddy C. Hsueh, +4

European Journal of Immunology

Lymphocyte DevelopmentAdaptive Immune SystemT-regulatory CellImmunologyImmune Regulation +24