Brett L. Knolhoff

CSF1/CSF1R Blockade Reprograms Tumor-Infiltrating Macrophages and Improves Response to T-cell Checkpoint Immunotherapy in Pancreatic Cancer Models

Yu Zhu, Brett L. Knolhoff, Melissa A. Meyer et al. · Cancer Research · 2014 · 1.3K citations · Full text

Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy

Hong Jiang, Samarth Hegde, Brett L. Knolhoff et al. · Nature Medicine · 2016 · 991 citations · Full text

Oncology, Pancreatic Cancer, Medicine +6

Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses

Jonathan B. Mitchem, Donal J. Brennan, Brett L. Knolhoff et al. · Cancer Research · 2012 · 929 citations · Full text

Immunology, Biological Microenvironments, Immunoediting +20

Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression

Yu Zhu, John M. Herndon, Dorothy K. Sojka et al. · Immunity · 2017 · 764 citations · Full text

Pancreatic Cancer, Promote Tumor Progression, Tissue-resident Macrophages +8

Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis

Megan K. Ruhland, Andrew J. Loza, Aude-Hélène Capietto et al. · Nature Communications · 2016 · 452 citations · Full text