Verastem (United States)

Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy

Hong Jiang, Samarth Hegde, Brett L. Knolhoff et al. · Nature Medicine · 2016 · 991 citations · Full text

Oncology, Pancreatic Cancer, Medicine +6

Nuclear FAK Controls Chemokine Transcription, Tregs, and Evasion of Anti-tumor Immunity

Alan Serrels, Tom Lund, Bryan Serrels et al. · Cell · 2015 · 405 citations · Full text

The phase 3 DUO trial: duvelisib vs ofatumumab in relapsed and refractory CLL/SLL

Ian W. Flinn, Peter Hillmen, Marco Montillo et al. · Blood · 2018 · 331 citations · Full text

Activity of the PI3K-δ,γ inhibitor duvelisib in a phase 1 trial and preclinical models of T-cell lymphoma

Steven M. Horwitz, Raphael Koch, Pierluigi Porcu et al. · Blood · 2017 · 274 citations · Full text

DYNAMO: A Phase II Study of Duvelisib (IPI-145) in Patients With Refractory Indolent Non-Hodgkin Lymphoma

Ian W. Flinn, Carole B. Miller, Kirit M. Ardeshna et al. · Journal of Clinical Oncology · 2019 · 257 citations · Full text