Leonie A. Cluse

Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis

Mai Nguyen, Richard Marcellus, Anne Roulston et al. · Proceedings of the National Academy of Sciences · 2007 · 652 citations · Full text

Medicine, Oncology, Pharmacology +17

Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53

Megan J. Bywater, Gretchen Poortinga, Elaine Sanij et al. · Cancer Cell · 2012 · 560 citations · Full text

Life Sciences, Molecular Biology, Oncology +16

Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3

Andrew W. Roberts, Lorraine Robb, Steven Rakar et al. · Proceedings of the National Academy of Sciences · 2001 · 302 citations · Full text

Life Sciences, Anatomy, Developmental Biology +17

BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1

Simon J. Hogg, Stephin J. Vervoort, Sumit Deswal et al. · Cell Reports · 2017 · 300 citations · Full text

Medicine, Immunology, Oncology +17

SOCS3 Is a Critical Physiological Negative Regulator of G-CSF Signaling and Emergency Granulopoiesis

Ben A. Croker, Donald Metcalf, Lorraine Robb et al. · Immunity · 2004 · 283 citations · Full text

Life Sciences, Cell Biology, Immunology +10