Debbie Swing

ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43

Eveline S. Arnold, Shuo‐Chien Ling, Stephanie C. Huelga et al. · Proceedings of the National Academy of Sciences · 2013 · 496 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss

Yunjong Lee, Senthilkumar S. Karuppagounder, Joo‐Ho Shin et al. · Nature Neuroscience · 2013 · 215 citations · Full text

Life Sciences, Neurobiology, Neuroscience +12

Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis

Shuo‐Chien Ling, Somasish Ghosh Dastidar, Seiya Tokunaga et al. · eLife · 2019 · 91 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative

Andrew T.N. Tebbenkamp, Cameron Green, Guilian Xu et al. · Human Molecular Genetics · 2011 · 41 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Overexpression of Parkinson’s Disease-Associated Mutation LRRK2 G2019S in Mouse Forebrain Induces Behavioral Deficits and α-Synuclein Pathology

Yulan Xiong, Stewart Neifert, Senthilkumar S. Karuppagounder et al. · eNeuro · 2017 · 39 citations · Full text

Life Sciences, Neurology, Neuroscience +17