Peter Bouwman

PARP Inhibitor Efficacy Depends on CD8+ T-cell Recruitment via Intratumoral STING Pathway Activation in BRCA-Deficient Models of Triple-Negative Breast Cancer

Constantia Pantelidou, Olmo Sonzogni, Mateus de Oliveira Taveira et al. · Cancer Discovery · 2019 · 649 citations · Full text

REV7 counteracts DNA double-strand break resection and affects PARP inhibition

Guotai Xu, J. Ross Chapman, Inger Brandsma et al. · Nature · 2015 · 583 citations · Full text

Chromatin, Genome Instability, Parp Inhibition +6

Autotaxin, a Secreted Lysophospholipase D, Is Essential for Blood Vessel Formation during Development

Laurens A. van Meeteren, Paula Ruurs, Catelijne Stortelers et al. · Molecular and Cellular Biology · 2006 · 529 citations · Full text

Secreted Lysophospholipase D, Developmental Biology, Signal Transduction +15

BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival

Chiara Gorrini, Pegah S. Baniasadi, Isaac S. Harris et al. · The Journal of Experimental Medicine · 2013 · 281 citations · Full text

Cell Death, Cancer Biology, Redox Biology +18

BRCA1 RING Function Is Essential for Tumor Suppression but Dispensable for Therapy Resistance

Rinske Drost, Peter Bouwman, Sven Rottenberg et al. · Cancer Cell · 2011 · 262 citations · Full text

Tumor Biology, Oncology, Medicine +10