Constantia Pantelidou

PARP Inhibitor Efficacy Depends on CD8+ T-cell Recruitment via Intratumoral STING Pathway Activation in BRCA-Deficient Models of Triple-Negative Breast Cancer

Constantia Pantelidou, Olmo Sonzogni, Mateus de Oliveira Taveira et al. · Cancer Discovery · 2019 · 649 citations · Full text

A first-in-class polymerase theta inhibitor selectively targets homologous-recombination-deficient tumors

Jia Zhou, Camille Gelot, Constantia Pantelidou et al. · Nature Cancer · 2021 · 320 citations · Full text

Molecular Biology, Cancer Genetics, Medicine +3

Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer

Anita K. Mehta, Emily Cheney, Christina Hartl et al. · Nature Cancer · 2020 · 239 citations · Full text

Breast Oncology, Medicine, Immunology +8

EZH2 inhibition activates a dsRNA–STING–interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer

Katherine L. Morel, Anjali V. Sheahan, Deborah L. Burkhart et al. · Nature Cancer · 2021 · 228 citations · Full text

Ezh2 Inhibition, Dsrna–sting–interferon Stress, Medicine +6

The Novel Oncolytic Adenoviral Mutant Ad5-3Δ-A20T Retargeted to αvβ6 Integrins Efficiently Eliminates Pancreatic Cancer Cells

Y. K. Stella Man, James A. Davies, Lynda Coughlan et al. · Molecular Cancer Therapeutics · 2018 · 48 citations · Full text