Isaac S. Harris

Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression

Isaac S. Harris, Aislinn E. Treloar, Satoshi Inoue et al. · Cancer Cell · 2015 · 948 citations · Full text

Reductive Stress, Tumor Biology, Chemoprevention Strategy +10

IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics

Masato Sasaki, Christiane B. Knobbe‐Thomsen, Joshua Munger et al. · Nature · 2012 · 506 citations · Full text

Somatic Variant, Medicine, Genetics +5

Glutathione Primes T Cell Metabolism for Inflammation

Tak W. Mak, Melanie Grusdat, Gordon S. Duncan et al. · Immunity · 2017 · 500 citations · Full text

Inflammation, Autoimmune Disease, Allergy +7

Non-canonical Glutamate-Cysteine Ligase Activity Protects against Ferroptosis

Yun Pyo Kang, Andrea Mockabee‐Macias, Chang Jiang et al. · Cell Metabolism · 2020 · 319 citations · Full text

Biochemistry, Metalloprotein, Medicine +3

D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function

Masato Sasaki, Christiane B. Knobbe‐Thomsen, Momoe Itsumi et al. · Genes & Development · 2012 · 296 citations · Full text