Christiane B. Knobbe‐Thomsen

Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression

Isaac S. Harris, Aislinn E. Treloar, Satoshi Inoue et al. · Cancer Cell · 2015 · 948 citations · Full text

Reductive Stress, Tumor Biology, Chemoprevention Strategy +10

IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics

Masato Sasaki, Christiane B. Knobbe‐Thomsen, Joshua Munger et al. · Nature · 2012 · 506 citations · Full text

Somatic Variant, Medicine, Genetics +5

Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling

Marc Zuckermann, Volker Hovestadt, Christiane B. Knobbe‐Thomsen et al. · Nature Communications · 2015 · 297 citations · Full text

D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function

Masato Sasaki, Christiane B. Knobbe‐Thomsen, Momoe Itsumi et al. · Genes & Development · 2012 · 296 citations · Full text

EGFR Phosphorylates Tumor-Derived EGFRvIII Driving STAT3/5 and Progression in Glioblastoma

Qi-Wen Fan, Christine Cheng, W. Clay Gustafson et al. · Cancer Cell · 2013 · 262 citations · Full text

Neuro-oncology, Signaling Pathway, Glioma +6