27-Hydroxycholesterol Links Hypercholesterolemia and Breast Cancer Pathophysiology

Erik R. Nelson, Suzanne E. Wardell, Jeff S. Jasper, +10

Science

Tumor BiologyBreast OncologyOncology27-Hydroxycholesterol Links HypercholesterolemiaMedicine +9

Systematic identification of signaling pathways with potential to confer anticancer drug resistance

Colin A. Martz, Kathleen Ottina, Katherine R. Singleton, +16

Science Signaling

Drug TargetBreast OncologyCancer BiologyTamoxifen SensitivityTumor Biology +21

ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer

Sung Hee Park, Ching‐yi Chang, Rachid Safi, +10

Cell Reports

The Metabolic Regulator ERRα, a Downstream Target of HER2/IGF-1R, as a Therapeutic Target in Breast Cancer

Ching‐yi Chang, Dmitri Kazmin, Jeff S. Jasper, +3

Cancer Cell

Tumor BiologyRadiation OncologyBreast OncologyEndocrine-related CancerMedicine +10

Obesity, Cholesterol Metabolism, and Breast Cancer Pathogenesis

Donald P. McDonnell, Sung Hee Park, Matthew T. Goulet, +6

Cancer Research

Breast OncologyPathologyTumor BiologyObesityMetabolic Syndrome +14

The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer

Kimberly J. Cocce, Jeff S. Jasper, Taylor K. Desautels, +29

Cell Reports

Breast OncologyCancer BiologyMammary Gland DevelopmentTumor BiologyTranscriptional Regulation +14

Lysine-Specific Histone Demethylase 1 Inhibitors Control Breast Cancer Proliferation in ERα-Dependent and -Independent Manners

Julie A. Pollock, Michelle D. Larrea, Jeff S. Jasper, +2

ACS Chemical Biology

Histone ModificationsBreast OncologyEstrogen ReceptorCancer BiologyTumor Biology +19

MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer

Xin Xu, Yun Zhang, Jeff S. Jasper, +6

Oncotarget

A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency

Wendell Jones, Binsheng Gong, Natalia Novoradovskaya, +71

Genome biology

ABL kinases promote breast cancer osteolytic metastasis by modulating tumor-bone interactions through TAZ and STAT5 signaling

Jun Wang, Clay Rouse, Jeff S. Jasper, +1

Science Signaling