Rachid Safi

Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells

John P. Chute, Garrett G. Muramoto, John G. Whitesides et al. · Proceedings of the National Academy of Sciences · 2006 · 464 citations · Full text

Life Sciences, Cell Biology, Hematology +17

Ligand binding was acquired during evolution of nuclear receptors

Héctor Escrivá, Rachid Safi, Catherine Hänni et al. · Proceedings of the National Academy of Sciences · 1997 · 401 citations · Full text

Life Sciences, Evolutionary Biology, Molecular Biology +17

Dysregulated cholesterol homeostasis results in resistance to ferroptosis increasing tumorigenicity and metastasis in cancer

Wen Liu, Binita Chakraborty, Rachid Safi et al. · Nature Communications · 2021 · 339 citations · Full text

Medicine, Cancer Biology, Oncology +17

Disulfiram (DSF) acts as a copper ionophore to induce copper‐dependent oxidative stress and mediate anti‐tumor efficacy in inflammatory breast cancer

Jennifer L. Allensworth, Myron K. Evans, François Bertucci et al. · Molecular Oncology · 2015 · 238 citations · Full text

Medicine, Oncology, Pharmacology +10

Unexpected Novel Relational Links Uncovered by Extensive Developmental Profiling of Nuclear Receptor Expression

Stéphanie Bertrand, Bernard Thisse, Raquel Tavares et al. · PLoS Genetics · 2007 · 205 citations · Full text

Life Sciences, Developmental Biology, Molecular Biology +17