Dysregulated cholesterol homeostasis results in resistance to ferroptosis increasing tumorigenicity and metastasis in cancer

Wen Liu, Binita Chakraborty, Rachid Safi, +3

Nature Communications

lncRNA ITGB8-AS1 functions as a ceRNA to promote colorectal cancer growth and migration through integrin-mediated focal adhesion signaling

Xiaoting Lin, Shiwen Zhuang, Chen Xue, +10

Molecular Therapy

CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer

Mahmoud A. Alfaqih, Erik R. Nelson, Wen Liu, +11

Cancer Research

Inhibition of TBK1 attenuates radiation-induced epithelial–mesenchymal transition of A549 human lung cancer cells via activation of GSK-3β and repression of ZEB1

Wen Liu, Yijuan Huang, Cong Liu, +7

Laboratory Investigation

Tumor BiologyRadiation MedicineRadiation-induced Epithelial–mesenchymal TransitionCell RegulationMedicine +9

miR-98 suppresses melanoma metastasis through a negative feedback loop with its target gene IL-6

Fei Li, Xin-ji Li, Li Qiao, +7

Experimental & Molecular Medicine

Up-Regulated Expression of miR-23a/b Targeted the Pro-Apoptotic Fas in Radiation-Induced thymic Lymphoma

Bailong Li, Mingjuan Sun, Fu Gao, +6

Cellular Physiology and Biochemistry

MALAT1 regulates miR-34a expression in melanoma cells

Fei Li, Xinji Li, Li Qiao, +3

Cell Death and Disease

Interrogation of nonconserved human adipose lincRNAs identifies a regulatory role of <i>linc-ADAL</i> in adipocyte metabolism

Xuan Zhang, Chenyi Xue, Jennie Lin, +16

Science Translational Medicine

Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer

Sung Hee Park, Rachid Safi, Xiaojing Liu, +6

Cell Reports

Cacalol, a natural sesquiterpene, induces apoptosis in breast cancer cells by modulating Akt-SREBP-FAS signaling pathway

Wen Liu, Eiji Furuta, Kazutoshi Shindo, +13

Breast Cancer Research and Treatment

Signal TransductionNatural SesquiterpeneChemoprevention StrategyMedicineApoptosis +8