Isabella Spinello

A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis

Catherine Labbaye, Isabella Spinello, Maria Teresa Quaranta et al. · Nature Cell Biology · 2008 · 225 citations

Three-step Pathway, Gene Regulation, Small Rna +3

MicroRNA-146a and AMD3100, two ways to control CXCR4 expression in acute myeloid leukemias

Isabella Spinello, Maria Teresa Quaranta, Roberta Riccioni et al. · Blood Cancer Journal · 2011 · 57 citations · Full text

Hematological Malignancy, Tumor Biology, Cxcr4 Regulation +12

Targeting Lactate Metabolism by Inhibiting MCT1 or MCT4 Impairs Leukemic Cell Proliferation, Induces Two Different Related Death-Pathways and Increases Chemotherapeutic Sensitivity of Acute Myeloid Leukemia Cells

Ernestina Saulle, Isabella Spinello, Maria Teresa Quaranta et al. · Frontiers in Oncology · 2021 · 49 citations · Full text

Chemoprevention Strategy, Mixed-phenotype Acute Leukemia, Apoptosis +18

The small-molecule compound AC-73 targeting CD147 inhibits leukemic cell proliferation, induces autophagy and increases the chemotherapeutic sensitivity of acute myeloid leukemia cells

Isabella Spinello, Ernestina Saulle, Maria Teresa Quaranta et al. · Haematologica · 2018 · 48 citations · Full text

Immunology, Cell Proliferation, Tumor Biology +16

CD147 Targeting by AC-73 Induces Autophagy and Reduces Intestinal Fibrosis Associated with TNBS Chronic Colitis

Alessia Butera, Maria Teresa Quaranta, Luca Crippa et al. · Journal of Crohn s and Colitis · 2022 · 32 citations · Full text