The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

Désirée Bonci, Valeria Coppola, Maria Musumeci, +11

Nature Medicine

Tumor BiologyTranscriptional RegulationRadiation OncologyOncologyEngineering +12

A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis

Catherine Labbaye, Isabella Spinello, Maria Teresa Quaranta, +11

Nature Cell Biology

Three-step PathwayGene RegulationSmall RnaGene ExpressionMedicine +1

Differential expression and functional role of GATA-2, NF-E2, and GATA-1 in normal adult hematopoiesis.

Catherine Labbaye, M Valtieri, Tiziano Barberi, +6

Journal of Clinical Investigation

GeneticsImmunologyRetinoic AcidBlood CellFunctional Role +16

Retinoic acid downmodulates erythroid differentiation and GATA1 expression in purified adult-progenitor culture

Catherine Labbaye, M Valtieri, Ugo Testa, +7

Blood

Role of PLZF in melanoma progression

Federica Felicetti, Lisabianca Bottero, Nadia Felli, +6

Oncogene

MelanomaMelanoma ProgressionDermatologyMedicineCancer Research +2

PLZF induces megakaryocytic development, activates Tpo receptor expression and interacts with GATA1 protein

Catherine Labbaye, Maria Teresa Quaranta, Alfredo Pagliuca, +4

Oncogene

Gata1 ProteinMolecular PhysiologySignal TransductionDevelopmental BiologySignaling Pathway +7

MicroRNA-146a and AMD3100, two ways to control CXCR4 expression in acute myeloid leukemias

Isabella Spinello, Maria Teresa Quaranta, Roberta Riccioni, +8

Blood Cancer Journal

Hematological MalignancyTumor BiologyCxcr4 RegulationCxcr4 ExpressionCxcr4 Protein Expression +10

Targeting Lactate Metabolism by Inhibiting MCT1 or MCT4 Impairs Leukemic Cell Proliferation, Induces Two Different Related Death-Pathways and Increases Chemotherapeutic Sensitivity of Acute Myeloid Leukemia Cells

Ernestina Saulle, Isabella Spinello, Maria Teresa Quaranta, +10

Frontiers in Oncology

Chemoprevention StrategyMixed-phenotype Acute LeukemiaApoptosisCell DeathMct4 Expression +16

The small-molecule compound AC-73 targeting CD147 inhibits leukemic cell proliferation, induces autophagy and increases the chemotherapeutic sensitivity of acute myeloid leukemia cells

Isabella Spinello, Ernestina Saulle, Maria Teresa Quaranta, +7

Haematologica

ImmunologyCell ProliferationTumor BiologyMyeloid NeoplasiaHematological Malignancy +14

Wegener autoantigen and myeloblastin are encoded by a single mRNA.

Catherine Labbaye, Philippe Musette, Y E Cayre

Proceedings of the National Academy of Sciences

Mixed-phenotype Acute LeukemiaGeneticsImmunologyProteasomeEpigenetics +17