Andrea Treyer

Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery

André Mateus, Laurie Gordon, Gareth Wayne et al. · Proceedings of the National Academy of Sciences · 2017 · 95 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +10

Intracellular drug bioavailability: a new predictor of system dependent drug disposition

André Mateus, Andrea Treyer, Christine Wegler et al. · Scientific Reports · 2017 · 82 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids

Andrea Treyer, André Mateus, Jacek R. Wiśniewski et al. · Molecular Pharmaceutics · 2018 · 39 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Hepatocyte size fractionation allows dissection of human liver zonation

Magnus Ölander, Christine Wegler, Inken Flörkemeier et al. · Journal of Cellular Physiology · 2021 · 24 citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

4-(Difluoromethyl)-5-(4-((3<i>R</i>,5<i>S</i>)-3,5-dimethylmorpholino)-6-((<i>R</i>)-3-methylmorpholino)-1,3,5-triazin-2-yl)pyridin-2-amine (PQR626), a Potent, Orally Available, and Brain-Penetrant mTOR Inhibitor for the Treatment of Neurological Disorders

Chiara Borsari, Erhan Keleş, Denise Rageot et al. · Journal of Medicinal Chemistry · 2020 · 22 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14