Christine Wegler

Variability in Mass Spectrometry-based Quantification of Clinically Relevant Drug Transporters and Drug Metabolizing Enzymes

Christine Wegler, Fabienne Z. Gaugaz, Tommy B. Andersson et al. · Molecular Pharmaceutics · 2017 · 118 citations · Full text

Metabolomic Profiling, Drug Purity, Bioanalysis +22

Global variability analysis of mRNA and protein concentrations across and within human tissues

Christine Wegler, Magnus Ölander, Jacek R. Wiśniewski et al. · NAR Genomics and Bioinformatics · 2019 · 98 citations · Full text

Engineering, Genetics, Multiomics +18

Intracellular drug bioavailability: a new predictor of system dependent drug disposition

André Mateus, Andrea Treyer, Christine Wegler et al. · Scientific Reports · 2017 · 75 citations · Full text

Direct Quantification of Cytochromes P450 and Drug Transporters—A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates

Helen Hammer, Kathrin Klein, Hannes Planatscher et al. · Drug Metabolism and Disposition · 2018 · 45 citations · Full text

A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies

Maria Karlgren, Ivailo Simoff, Maria Backlund et al. · Journal of Pharmaceutical Sciences · 2017 · 43 citations

Improved Tool, Natural Sciences, Molecular Biology +10