Saara Laulumaa

Atomic resolution view into the structure–function relationships of the human myelin peripheral membrane protein P2

Salla Ruskamo, Ravi Prakash Yadav, Satyan Sharma et al. · Acta Crystallographica Section D Biological Crystallography · 2013 · 55 citations · Full text

Life Sciences, Biochemistry, Biophysics +17

Enhancing Action of Positive Allosteric Modulators through the Design of Dimeric Compounds

Thomas Drapier, Pierre Geubelle, Charlotte Bouckaert et al. · Journal of Medicinal Chemistry · 2018 · 49 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure and interactions of the endogenous human Commander complex

Saara Laulumaa, Esa‐Pekka Kumpula, Juha T. Huiskonen et al. · Nature Structural & Molecular Biology · 2024 · 49 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

7-Phenoxy-Substituted 3,4-Dihydro-2<i>H</i>-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency

Eric Goffin, Thomas Drapier, A.P. Larsen et al. · Journal of Medicinal Chemistry · 2017 · 48 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Determinants of ligand binding and catalytic activity in the myelin enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase

Arne Raasakka, Matti Myllykoski, Saara Laulumaa et al. · Scientific Reports · 2015 · 35 citations · Full text

Life Sciences, Biochemistry, Enzyme Mechanism +13