A.P. Larsen

7-Phenoxy-Substituted 3,4-Dihydro-2<i>H</i>-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency

Eric Goffin, Thomas Drapier, A.P. Larsen et al. · Journal of Medicinal Chemistry · 2017 · 48 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Chemoenzymatic Synthesis of New 2,4-<i>syn</i>-Functionalized (<i>S</i>)-Glutamate Analogues and Structure–Activity Relationship Studies at Ionotropic Glutamate Receptors and Excitatory Amino Acid Transporters

Zeinab Assaf, A.P. Larsen, Raminta Venskutonytė et al. · Journal of Medicinal Chemistry · 2013 · 43 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Synthesis and Pharmacology of Mono-, Di-, and Trialkyl-Substituted 7-Chloro-3,4-dihydro-2<i>H</i>-1,2,4-benzothiadiazine 1,1-Dioxides Combined with X-ray Structure Analysis to Understand the Unexpected Structure–Activity Relationship at AMPA Receptors

A.P. Larsen, Pierre Francotte, Karla Frydenvang et al. · ACS Chemical Neuroscience · 2016 · 31 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Identification and Structure-Function Study of Positive Allosteric Modulators of Kainate Receptors

A.P. Larsen, Sabine Fièvre, Karla Frydenvang et al. · Molecular Pharmacology · 2017 · 31 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Molecular Recognition of Two 2,4‐<i>syn</i>‐Functionalized (<i>S</i>)‐Glutamate Analogues by the Kainate Receptor GluK3 Ligand Binding Domain

Raminta Venskutonytė, A.P. Larsen, Karla Frydenvang et al. · ChemMedChem · 2014 · 12 citations

Medicine, Medicinal Chemistry, Pharmacology +17