Chris J. Frangieh

A molecular single-cell lung atlas of lethal COVID-19

Johannes C. Melms, Jana Biermann, Huachao Huang et al. · Nature · 2021 · 693 citations · Full text

Lethal Covid-19, Respiratory Infection, Covid-19 +1

Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion

Chris J. Frangieh, Johannes C. Melms, Pratiksha I. Thakore et al. · Nature Genetics · 2021 · 245 citations · Full text

Tumor Biology, Immune Evasion, Cancer Immune Evasion +11

Scalable genetic screening for regulatory circuits using compressed Perturb-seq

Douglas Yao, Loïc Binan, Jon Bezney et al. · Nature Biotechnology · 2023 · 89 citations · Full text

The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity

Patricia Ho, Johannes C. Melms, Meri Rogava et al. · Cancer Cell · 2023 · 84 citations · Full text

Cancer Immunosurveillance, Cd58-cd2 Axis, Immunology +11

Cell type-specific delivery by modular envelope design

Daniel Strebinger, Chris J. Frangieh, Mirco Friedrich et al. · Nature Communications · 2023 · 75 citations · Full text

Tissue Engineering, Engineering, Immunology +17