Analisa Thompson Gray

Development and Antiparkinsonian Activity of VU0418506, a Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor 4 Homomers without Activity at mGlu_2/4 Heteromers

Colleen M. Niswender, Carrie K. Jones, Xin Lin et al. · ACS Chemical Neuroscience · 2016 · 58 citations

Medicine, Neuroscience, Pharmacology +17

Discovery of <i>N</i>-(5-Fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide (VU0424238): A Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Selected for Clinical Evaluation

Andrew S. Felts, Alice L. Rodriguez, Anna L. Blobaum et al. · Journal of Medicinal Chemistry · 2017 · 30 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Discovery, Structure–Activity Relationship, and Biological Characterization of a Novel Series of 6-((1<i>H</i>-Pyrazolo[4,3-<i>b</i>]pyridin-3-yl)amino)-benzo[<i>d</i>]isothiazole-3-carboxamides as Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 4 (mGlu₄)

Sean R. Bollinger, Darren W. Engers, Joseph D. Panarese et al. · Journal of Medicinal Chemistry · 2018 · 26 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Gβγ-SNAP25 exocytotic brake removal enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity

Ryan P. Ceddia, Zack Zurawski, Analisa Thompson Gray et al. · Journal of Clinical Investigation · 2023 · 16 citations · Full text

Life Sciences, Endocrinology, Physiology +17

Discovery of imidazo[1,2-a]-, [1,2,4]triazolo[4,3-a]-, and [1,2,4]triazolo[1,5-a]pyridine-8-carboxamide negative allosteric modulators of metabotropic glutamate receptor subtype 5

Andrew S. Felts, Alice L. Rodriguez, Ryan D. Morrison et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 10 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12