Firoz Roshan Kurudenkandy

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

Samuel I. A. Cohen, Paolo Arosio, Jenny Presto et al. · Nature Structural & Molecular Biology · 2015 · 424 citations

Life Sciences, Biochemistry, Molecular Biology +16

Spreading of Neurodegenerative Pathology via Neuron-to-Neuron Transmission of  -Amyloid

Sangeeta Nath, Lotta Agholme, Firoz Roshan Kurudenkandy et al. · Journal of Neuroscience · 2012 · 243 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Amyloid-β-Induced Action Potential Desynchronization and Degradation of Hippocampal Gamma Oscillations Is Prevented by Interference with Peptide Conformation Change and Aggregation

Firoz Roshan Kurudenkandy, Misha Zilberter, Henrik Biverstål et al. · Journal of Neuroscience · 2014 · 109 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Dementia-related Bri2 BRICHOS is a versatile molecular chaperone that efficiently inhibits Aβ42 toxicity in <i>Drosophila</i>

Helen Poska, Martin Haslbeck, Firoz Roshan Kurudenkandy et al. · Biochemical Journal · 2016 · 56 citations

Life Sciences, Biochemistry, Neuroscience +16

Bri2 BRICHOS chaperone rescues impaired fast-spiking interneuron behavior and neuronal network dynamics in an AD mouse model in vitro

Yuniesky Andrade‐Talavera, Gefei Chen, Firoz Roshan Kurudenkandy et al. · Neurobiology of Disease · 2021 · 19 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17