Patricia McCoon

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

Michael Hedvat, Dennis Huszar, Andreas Herrmann et al. · Cancer Cell · 2009 · 526 citations · Full text

Tumor Biology, Signaling Pathway, Solid Tumors +8

<i>Drosophila unpaired</i> encodes a secreted protein that activates the JAK signaling pathway

Douglas A. Harrison, Patricia McCoon, Richard Binari et al. · Genes & Development · 1998 · 388 citations · Full text

STAT3 antisense oligonucleotide AZD9150 in a subset of patients with heavily pretreated lymphoma: results of a phase 1b trial

Matthew J. Reilley, Patricia McCoon, Carl Cook et al. · Journal for ImmunoTherapy of Cancer · 2018 · 275 citations · Full text

A Human Monoclonal Anti-ANG2 Antibody Leads to Broad Antitumor Activity in Combination with VEGF Inhibitors and Chemotherapy Agents in Preclinical Models

Jeffrey L. Brown, Zhe Cao, Maria Pinzon-Ortiz et al. · Molecular Cancer Therapeutics · 2010 · 150 citations · Full text

Immunology, Vegf Inhibitors, Tumor Biology +16

Antibody-Mediated Blockade of Integrin αvβ6 Inhibits Tumor Progression <i>In vivo</i> by a Transforming Growth Factor-β–Regulated Mechanism

Louise A. Koopman Van Aarsen, Diane R. Leone, Steffan N. Ho et al. · Cancer Research · 2008 · 140 citations · Full text

Detroit 562, Antibody-mediated Blockade, Immunology +13