In Vitro–expanded Antigen-specific Regulatory T Cells Suppress Autoimmune Diabetes

Qizhi Tang, Kammi Henriksen, Mingying Bi, +6

The Journal of Experimental Medicine

Anergic PhenotypeT-regulatory CellImmunologyRegulatory T CellsImmunotherapy +15

Type 1 diabetes immunotherapy using polyclonal regulatory T cells

Jeffrey A. Bluestone, Jane H. Buckner, Mark Fitch, +15

Science Translational Medicine

Translational MedicineDiabetes ManagementAutoimmune DiseaseT-regulatory CellDiabetes +11

IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

Alana G. Lerner, John-Paul Upton, Paurush Praveen, +14

Cell Metabolism

InflammationIrremediable Er StressSignal TransductionThioredoxin-interacting ProteinSignaling Pathway +9

Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice

Qizhi Tang, Jason Y. Adams, Aaron J. Tooley, +7

Nature Immunology

Autoimmune DiseaseAutoimmune ResponsesT-regulatory CellDiabetesImmunology +7

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR–induced stop signal

Brian T. Fife, Kristen E. Pauken, Todd N. Eagar, +6

Nature Immunology

Signal TransductionMedicineImmunologyTolerance InductionPd-l1 Promote Tolerance +3

Central Role of Defective Interleukin-2 Production in the Triggering of Islet Autoimmune Destruction

Qizhi Tang, Jason Y. Adams, Cristina Peñaranda, +6

Immunity

InflammationCytokineCentral RoleIslet Autoimmune DestructionDefective Interleukin-2 Production +11

Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells

Qizhi Tang, Kammi Henriksen, Elisa K. Boden, +6

The Journal of Immunology

Loss of integrin αvβ8 on dendritic cells causes autoimmunity and colitis in mice

Mark A. Travis, Boris Reizis, Andrew C. Melton, +9

Nature

InflammationAutoimmune DiseaseAllergyMucosal ImmunologyIntegrin αVβ8 +8

IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells

Yenkel Grinberg‐Bleyer, Audrey Baeyens, Sylvaine You, +11

The Journal of Experimental Medicine

Distinct roles of CTLA‐4 and TGF‐β in CD4⁺CD25⁺ regulatory T cell function

Qizhi Tang, Elisa K. Boden, Kammi Henriksen, +3

European Journal of Immunology

Adaptive Immune SystemT-regulatory CellImmune RegulationImmunologyRegulatory T Cells +18