William E. Frietze

MEK inhibitors: The chemistry and biological activity of U0126, its analogs, and cyclization products

John V. Duncia, Joseph B. Santella, C. Anne Higley et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 406 citations · Full text

Life Sciences, Biochemistry, Pharmacology +11

Discovery of an Orally Active Series of Isoxazoline Glycoprotein IIb/IIIa Antagonists

Chu‐Biao Xue, John Wityak, Thais M. Sielecki et al. · Journal of Medicinal Chemistry · 1997 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans

Ruth Young-Sciame, F. Lee, Frank M. Nedza et al. · Drug Metabolism and Disposition · 2016 · 44 citations

Medicine, Biochemistry, Pharmacology +15

Orally Active Isoxazoline Glycoprotein IIb/IIIa Antagonists with Extended Duration of Action

Richard E. Olson, Thais M. Sielecki, John Wityak et al. · Journal of Medicinal Chemistry · 1999 · 35 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

CRF Ligands via suzuki and negishi couplings of 3-pyridyl boronic acids or halides with 2-benzyloxy-4-chloro-3-nitropyridine

Argyrios G. Arvanitis, Charles R. Arnold, Lawrence W. Fitzgerald et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 17 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +7