Ruth Young-Sciame

Synthesis and Biological Evaluation of Quinoline Salicylic Acids As P-Selectin Antagonists

Neelu Kaila, Kristin Janz, Silvano DeBernardo et al. · Journal of Medicinal Chemistry · 2006 · 122 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans

Ruth Young-Sciame, F. Lee, Frank M. Nedza et al. · Drug Metabolism and Disposition · 2016 · 44 citations

Medicine, Biochemistry, Pharmacology +15

Reactions of .alpha.-Acetoxy-N-nitrosopyrrolidine and .alpha.-Acetoxy-N-nitrosopiperidine with Deoxyguanosine: Formation of N2-Tetrahydrofuranyl and N2-Tetrahydropyranyl Adducts

Ruth Young-Sciame, Mingyao Wang, Fung‐Lung Chung et al. · Chemical Research in Toxicology · 1995 · 39 citations

Natural Sciences, Chemistry, Pharmacology +6

Desvenlafaxine and Venlafaxine Exert Minimal In Vitro Inhibition of Human Cytochrome P450 and P-Glycoprotein Activities

Aram Oganesian, Adam D. Shilling, Ruth Young-Sciame et al. · Psychopharmacology Bulletin · 2025 · 36 citations

Medicine, Pharmacokinetics, Pharmacology +17

Reaction of .alpha.-acetoxy-N-nitrosopiperidine with deoxyguanosine: oxygen-dependent formation of 4-oxo-2-pentenal and a 1,N2-ethenodeoxyguanosine adduct

Stephen S. Hecht, Ruth Young-Sciame, Fung Lung Chung · Chemical Research in Toxicology · 1992 · 33 citations

Natural Sciences, Chemistry, Pharmacology +9